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Intramolecular hydrogen transfer reactions of thiyl radicals from glutathione: formation of carbon-centered radical at Glu, Cys and Gly

Glutathione thiyl radicals (GS(•)) were generated in H(2)O and D(2)O by either exposure of GSH to AAPH(), photoirradiation of GSH in the presence of acetone, or photoirradiation of GSSG. Detailed interpretation of the fragmentation pathways of deuterated GSH and GSH-derivatives during mass spectrome...

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Detalhes bibliográficos
Main Authors: Mozziconacci, Olivier, Williams, Todd D., Schöneich, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736831/
https://ncbi.nlm.nih.gov/pubmed/22712461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3000494
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