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Chemical Synthesis of the Lantibiotic Lacticin 481 Reveals the Importance of Lanthionine Stereochemistry

[Image: see text] Lantibiotics are a family of antibacterial peptide natural products characterized by the post-translational installation of the thioether-containing amino acids lanthionine and methyllanthionine. Until recently, only a single naturally occurring stereochemical configuration for eac...

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Bibliographic Details
Main Authors: Knerr, Patrick J., van der Donk, Wilfred A.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2013
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736828/
https://ncbi.nlm.nih.gov/pubmed/23621626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4014024
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