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2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells

Mitotic defects leading to aneuploidy have been recognized as a hallmark of tumor cells for over 100 years. Current data indicate that ~85% of human cancers have missegregated chromosomes to become aneuploid. Some maintain a stable, aneuploid karyotype while others consistently missegregate chromoso...

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מידע ביבליוגרפי
Main Authors: Zasadil, Lauren M., Britigan, Eric M.C., Weaver, Beth A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736819/
https://ncbi.nlm.nih.gov/pubmed/23416057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2013.02.001
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