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2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells
Mitotic defects leading to aneuploidy have been recognized as a hallmark of tumor cells for over 100 years. Current data indicate that ~85% of human cancers have missegregated chromosomes to become aneuploid. Some maintain a stable, aneuploid karyotype while others consistently missegregate chromoso...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736819/ https://ncbi.nlm.nih.gov/pubmed/23416057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2013.02.001 |
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