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Expanded Granulocyte/Monocyte Compartment in Myeloid-Specific Triple Foxo Knockout Increases Oxidative Stress and Accelerates Atherosclerosis in Mice

RATIONALE: Increased neutrophil and monocyte counts are often associated with an increased risk of atherosclerosis, but their relationship to insulin sensitivity is unknown. OBJECTIVE: To investigate the contribution of forkhead transcription factors (FoxO) in myeloid cells to neutrophil and monocyt...

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Detalhes bibliográficos
Main Authors: Tsuchiya, Kyoichiro, Westerterp, Marit, Murphy, Andrew J., Subramanian, Vidya, Ferrante, Anthony W., Tall, Alan R., Accili, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736810/
https://ncbi.nlm.nih.gov/pubmed/23420833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.300749
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