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Repair of Chromosomal Double-Strand Breaks by Precise Ligation in Human Cells

Double-strand breaks (DSBs), a common type of DNA lesion, occur daily in human cells as a result of both endogenous and exogenous damaging agents. DSBs are repaired in two general ways: by the homology-dependent, error-free pathways of homologous recombination (HR) and by the homology-independent, e...

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Detalhes bibliográficos
Main Authors: Lin, William Y., Wilson, John H., Lin, Yunfu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736570/
https://ncbi.nlm.nih.gov/pubmed/23707303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.04.024
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