Carregant...

Are hERG Channel Blockers Also Phospholipidosis Inducers?

Both pharmacophore models of the human ether-à-go-go-related gene (hERG) channel blockers and phospholipidosis (PLD) inducers contain a hydrophobic moiety and a hydrophilic motif / positively charged center, so it is interesting to investigate the overlap between the ligand chemical spaces of both t...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Sun, Hongmao, Xia, Menghang, Shahane, Sampada A., Jadhav, Ajit, Austin, Christopher P., Huang, Ruili
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736554/
https://ncbi.nlm.nih.gov/pubmed/23856051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.06.034
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!