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Predicting and manipulating cardiac drug inactivation by the human gut bacterium Eggerthella lenta()
Despite numerous examples of the effects of the human gastrointestinal microbiome on drug efficacy and toxicity, there is often an incomplete understanding of the underlying mechanisms. Here, we dissect the inactivation of the cardiac drug digoxin by the gut Actinobacterium Eggerthella lenta. Transc...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736355/ https://ncbi.nlm.nih.gov/pubmed/23869020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1235872 |
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