Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria

Plant-derived lignans, consumed daily by most individuals, are thought to protect against cancer and other diseases(1); however, their bioactivity requires gut bacterial conversion to enterolignans(2). Here, we dissect a four-species bacterial consortium sufficient for all five reactions in this pat...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Bess, Elizabeth N., Bisanz, Jordan E., Yarza, Fauna, Bustion, Annamarie, Rich, Barry E., Li, Xingnan, Kitamura, Seiya, Waligurski, Emily, Ang, Qi Yan, Alba, Diana L., Spanogiannopoulos, Peter, Nayfach, Stephen, Koliwad, Suneil K., Wolan, Dennis W., Franke, Adrian A., Turnbaugh, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941677/
https://ncbi.nlm.nih.gov/pubmed/31686027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0596-1
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