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Mechanistic insight into digoxin inactivation by Eggerthella lenta augments our understanding of its pharmacokinetics
The human gut microbiota plays a key role in pharmacology, yet the mechanisms responsible remain unclear, impeding efforts toward personalized medicine. We recently identified a cytochrome-encoding operon in the common gut Actinobacterium Eggerthella lenta that is transcriptionally activated by the...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063850/ https://ncbi.nlm.nih.gov/pubmed/24637603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.27915 |
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