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G-Quadruplex structures are stable and detectable in human genomic DNA

The G-quadruplex is an alternative DNA structural motif that is considered to be functionally important in the mammalian genome for transcriptional regulation, DNA replication and genome stability, but the nature and distribution of G-quadruplexes across the genome remains elusive. Here, we address...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lam, Enid Yi Ni, Beraldi, Dario, Tannahill, David, Balasubramanian, Shankar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736099/
https://ncbi.nlm.nih.gov/pubmed/23653208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2792
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