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STAT6 controls the number of regulatory T cells in vivo thereby regulating allergic lung inflammation()
STAT6 plays a central role in IL-4-mediated allergic responses. Several studies indicate that regulatory T cells (Treg) can be modulated by IL-4 in vitro. We previously showed that STAT6(−/−) mice are highly resistant to allergic lung inflammation even when wild type Th2 effectors were provided and...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735779/ https://ncbi.nlm.nih.gov/pubmed/23825312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300486 |
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