Transfer of in vivo primed transgenic T cells supports allergic lung inflammation and FIZZ1 and Ym1 production in an IL-4Rα and STAT6 dependent manner

BACKGROUND: CD4+ T helper type 2 (T(H)2) cells, their cytokines IL-4, IL-5 and IL-13 and the transcription factor STAT6 are known to regulate various features of asthma including lung inflammation, mucus production and airway hyperreactivity and also drive alternative activation of macrophages (AAM)...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Dasgupta, Preeta, Chapoval, Svetlana P, Smith, Elizabeth P, Keegan, Achsah D
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212823/
https://ncbi.nlm.nih.gov/pubmed/22014099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-60
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk