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STAT6 controls the number of regulatory T cells in vivo thereby regulating allergic lung inflammation()

STAT6 plays a central role in IL-4-mediated allergic responses. Several studies indicate that regulatory T cells (Treg) can be modulated by IL-4 in vitro. We previously showed that STAT6(−/−) mice are highly resistant to allergic lung inflammation even when wild type Th2 effectors were provided and...

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Detalhes bibliográficos
Main Authors: Dorsey, Nicolas J., Chapoval, Svetlana P., Smith, Elizabeth P., Skupsky, Jonathan, Scott, David W., Keegan, Achsah D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735779/
https://ncbi.nlm.nih.gov/pubmed/23825312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300486
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