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Linking Stochastic Fluctuations in Chromatin Structure and Gene Expression

The number of mRNA and protein molecules expressed from a single gene molecule fluctuates over time. These fluctuations have been attributed, in part, to the random transitioning of promoters between transcriptionally active and inactive states, causing transcription to occur in bursts. However, the...

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Autori principali: Brown, Christopher R., Mao, Changhui, Falkovskaia, Elena, Jurica, Melissa S., Boeger, Hinrich
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735467/
https://ncbi.nlm.nih.gov/pubmed/23940458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001621
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