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Linking Stochastic Fluctuations in Chromatin Structure and Gene Expression

The number of mRNA and protein molecules expressed from a single gene molecule fluctuates over time. These fluctuations have been attributed, in part, to the random transitioning of promoters between transcriptionally active and inactive states, causing transcription to occur in bursts. However, the...

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Detalhes bibliográficos
Main Authors: Brown, Christopher R., Mao, Changhui, Falkovskaia, Elena, Jurica, Melissa S., Boeger, Hinrich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735467/
https://ncbi.nlm.nih.gov/pubmed/23940458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001621
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