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The N-terminal half of the connexin protein contains the core elements of the pore and voltage gates

Connexins form channels with large aqueous pores that mediate fluxes of inorganic ions and biological signaling molecules. Studies aimed at identifying the connexin pore now include a crystal structure that provides details of putative pore-lining residues that need to be verified using independent...

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Main Authors: Kronengold, Jack, Srinivas, Miduturu, Verselis, Vytas K.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735448/
https://ncbi.nlm.nih.gov/pubmed/22825713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-012-9457-z
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