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Conformational changes in a pore-forming region underlie voltage-dependent “loop gating” of an unapposed connexin hemichannel
The structure of the pore is critical to understanding the molecular mechanisms underlying selective permeation and voltage-dependent gating of channels formed by the connexin gene family. Here, we describe a portion of the pore structure of unapposed hemichannels formed by a Cx32 chimera, Cx32*Cx43...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713147/ https://ncbi.nlm.nih.gov/pubmed/19468074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910207 |
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