Prevalence of the variant allele rs61764370 T>G in the 3′UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer families

Recently, a variant allele in the 3′UTR of the KRAS gene (rs61764370 T>G) was shown to be associated with an increased risk for developing non-small cell lung cancer, as well as ovarian cancer, and was most enriched in ovarian cancer patients from hereditary breast and ovarian cancer families. Th...

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Autors principals: Hollestelle, Antoinette, Pelletier, Cory, Hooning, Maartje, Crepin, Ellen, Schutte, Mieke, Look, Maxime, Collee, J. Margriet, Nieuwlaat, Anja, Dorssers, Lambert C. J., Seynaeve, Caroline, Aulchenko, Yurii S., Martens, John W. M., van den Ouweland, Ans M. W., Weidhaas, Joanne B.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735357/
https://ncbi.nlm.nih.gov/pubmed/20676756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-1080-z
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