Variable association of reactive intermediate genes with systemic lupus erythematosus (SLE) in populations with different African ancestry

OBJECTIVE: Little is known about the genetic etiology of systemic lupus erythematosus (SLE) in individuals of African ancestry, despite its higher prevalence and greater disease severity. Overproduction of nitric oxide (NO) and reactive oxygen species are implicated in the pathogenesis and severity...

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Autori principali: Ramos, Paula S., Oates, James C., Kamen, Diane L., Williams, Adrienne H., Gaffney, Patrick M., Kelly, Jennifer A., Kaufman, Kenneth M., Kimberly, Robert P., Niewold, Timothy B., Jacob, Chaim O., Tsao, Betty P., Alarcón, Graciela S., Brown, Elizabeth E., Edberg, Jeffrey C., Petri, Michelle A., Ramsey-Goldman, Rosalind, Reveille, John D., Vilá, Luis M., James, Judith A., Guthridge, Joel M., Merrill, Joan T., Boackle, Susan A., Freedman, Barry I., Scofield, R. Hal, Stevens, Anne M., Vyse, Timothy J., Criswell, Lindsey A., Moser, Kathy L., Alarcón-Riquelme, Marta E., Langefeld, Carl D., Harley, John B., Gilkeson, Gary S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735344/
https://ncbi.nlm.nih.gov/pubmed/23637325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3899/jrheum.120989
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