Trans-Ancestral Studies Fine Map the SLE-Susceptibility Locus TNFSF4

We previously established an 80 kb haplotype upstream of TNFSF4 as a susceptibility locus in the autoimmune disease SLE. SLE-associated alleles at this locus are associated with inflammatory disorders, including atherosclerosis and ischaemic stroke. In Europeans, the TNFSF4 causal variants have rema...

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Autors principals: Manku, Harinder, Langefeld, Carl D., Guerra, Sandra G., Malik, Talat H., Alarcon-Riquelme, Marta, Anaya, Juan-Manuel, Bae, Sang-Cheol, Boackle, Susan A., Brown, Elizabeth E., Criswell, Lindsey A., Freedman, Barry I., Gaffney, Patrick M., Gregersen, Peter A., Guthridge, Joel M., Han, Sang-Hoon, Harley, John B., Jacob, Chaim O., James, Judith A., Kamen, Diane L., Kaufman, Kenneth M., Kelly, Jennifer A., Martin, Javier, Merrill, Joan T., Moser, Kathy L., Niewold, Timothy B., Park, So-Yeon, Pons-Estel, Bernardo A., Sawalha, Amr H., Scofield, R. Hal, Shen, Nan, Stevens, Anne M., Sun, Celi, Gilkeson, Gary S., Edberg, Jeff C., Kimberly, Robert P., Nath, Swapan K., Tsao, Betty P., Vyse, Tim J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715547/
https://ncbi.nlm.nih.gov/pubmed/23874208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003554
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