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Peripheral analgesic blockade of hypernociception: Activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K(+) channel pathway
The final step in the direct restoration of the nociceptor threshold by peripheral administration of morphine and dipyrone was recently suggested to result from the opening of ATP-sensitive K(+) channels ([Formula: see text]). This channel is known to be open either directly by cGMP or indirectly vi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373522/ https://ncbi.nlm.nih.gov/pubmed/14990791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308382101 |
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