Caricamento...
Chimeric molecules facilitate the degradation of androgen receptors and repress the growth of LNCaP cells
Post-translational degradation of protein plays an important role in cell life. We employed chimeric molecules (dihydrotestosterone-based proteolysis-targeting chimeric molecule [DHT-PROTAC]) to facilitate androgen receptor (AR) degradation via the ubiquitin–proteasome pathway (UPP) and to investiga...
Salvato in:
| Autori principali: | , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2009
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735208/ https://ncbi.nlm.nih.gov/pubmed/19050678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2008.26 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|