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Inhibition of neuronal phenotype by PTEN in PC12 cells

The mechanisms of neuronal differentiation in PC12 cells are still not completely understood. Here, we report that the tumor suppressor PTEN has a profound effect on differentiation by affecting several pathways involved in nerve growth factor (NGF) signaling. When overexpressed in PC12 cells, PTEN...

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Bibliografski detalji
Glavni autori: Musatov, Sergei, Roberts, Jill, Brooks, Andrew I., Pena, John, Betchen, Simone, Pfaff, Donald W., Kaplitt, Michael G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC373513/
https://ncbi.nlm.nih.gov/pubmed/14990793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308289101
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