Inhibition of neuronal phenotype by PTEN in PC12 cells

The mechanisms of neuronal differentiation in PC12 cells are still not completely understood. Here, we report that the tumor suppressor PTEN has a profound effect on differentiation by affecting several pathways involved in nerve growth factor (NGF) signaling. When overexpressed in PC12 cells, PTEN...

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Autores principales: Musatov, Sergei, Roberts, Jill, Brooks, Andrew I., Pena, John, Betchen, Simone, Pfaff, Donald W., Kaplitt, Michael G.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC373513/
https://ncbi.nlm.nih.gov/pubmed/14990793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308289101
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