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RNAi-mediated silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors

Estrogen receptor α (ERα) plays a major role in the regulation of neuroendocrine functions and behaviors by estrogens. Although the generation of ERα knockout mice advanced our knowledge of ERα functions, gene deletion using this method is global and potentially confounded by developmental consequen...

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Detalhes bibliográficos
Main Authors: Musatov, Sergei, Chen, Walter, Pfaff, Donald W., Kaplitt, Michael G., Ogawa, Sonoko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502479/
https://ncbi.nlm.nih.gov/pubmed/16803960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603045103
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