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Silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus leads to metabolic syndrome

Estrogen receptor α (ERα) plays a pivotal role in the regulation of food intake and energy expenditure by estrogens. Although it is well documented that a disruption of ERα signaling in ERα knockout (ERKO) mice leads to an obese phenotype, the sites of estrogen action and mechanisms underlying this...

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Detalhes bibliográficos
Main Authors: Musatov, Sergei, Chen, Walter, Pfaff, Donald W., Mobbs, Charles V., Yang, Xue-Jun, Clegg, Deborah J., Kaplitt, Michael G., Ogawa, Sonoko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892990/
https://ncbi.nlm.nih.gov/pubmed/17284595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610787104
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