Expressional analysis of the astrocytic Kir4.1 channel in a pilocarpine–induced temporal lobe epilepsy model

The inwardly rectifying potassium (Kir) channel Kir4.1 in brain astrocytes mediates spatial K(+) buffering and regulates neural activities. Recent studies have shown that loss-of-function mutations in the human gene KCNJ10 encoding Kir4.1 cause epileptic seizures, suggesting a close relationship bet...

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Autori principali: Nagao, Yuki, Harada, Yuya, Mukai, Takahiro, Shimizu, Saki, Okuda, Aoi, Fujimoto, Megumi, Ono, Asuka, Sakagami, Yoshihisa, Ohno, Yukihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734973/
https://ncbi.nlm.nih.gov/pubmed/23922547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00104
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