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Transmembrane protein domains rarely use covalent domain recombination as an evolutionary mechanism
Recombination of evolutionarily unrelated domains is a mechanism often used by evolution to produce variety in soluble proteins. By using a classification of polytopic transmembrane domains into families, we examined integral membrane proteins for evidence of this mechanism. Surprisingly, we found t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373490/ https://ncbi.nlm.nih.gov/pubmed/14993608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307330101 |
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