Downregulation of Mcl-1 through inhibition of translation contributes to benzyl isothiocyanate-induced cell cycle arrest and apoptosis in human leukemia cells

Benzyl isothiocyanate (BITC) is one of the compounds of ITCs' family that has attracted a great deal of interest because of its ability to exhibit anticancer activity. In this study, we investigated the effects of BITC on cell cycle arrest and apoptosis in human leukemia cell lines, primary leu...

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Autors principals: Zhou, T, Li, G, Cao, B, Liu, L, Cheng, Q, Kong, H, Shan, C, Huang, X, Chen, J, Gao, N
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734843/
https://ncbi.nlm.nih.gov/pubmed/23449451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.41
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