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Identification of p53 regulators by genome-wide functional analysis
The p53 tumor-suppressor protein is a critical mediator of cellular growth arrest and the induction of apoptosis. To identify proteins involved in the modulation of p53 transcriptional activity, a gain-of-function cellular screen was carried out with an arrayed matrix of ≈20,000 cDNAs. Nine genes pr...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373483/ https://ncbi.nlm.nih.gov/pubmed/14990790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308562100 |
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