Synergistic Effects of GDNF and VEGF on Lifespan and Disease Progression in a Familial ALS Rat Model

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord. We have recently shown that human mesenchymal stem cells (hMSCs) modified to release glial cell line-derived neurotrophic factor (GDNF) decrea...

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Autors principals: Krakora, Dan, Mulcrone, Patrick, Meyer, Michael, Lewis, Christina, Bernau, Ksenija, Gowing, Genevieve, Zimprich, Chad, Aebischer, Patrick, Svendsen, Clive N, Suzuki, Masatoshi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734670/
https://ncbi.nlm.nih.gov/pubmed/23712039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.108
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