Gonadectomy and dehydroepiandrosterone (DHEA) do not modulate disease progression in the G93A mutant SOD1 rat model of amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized the progressive loss of brain and spinal cord motor neurons. Epidemiological studies have shown a higher incidence of ALS in men than women. Interestingly, there are clear gender differences in disease onset and p...

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Главные авторы: Hayes-Punzo, Antonio, Mulcrone, Patrick, Meyer, Michael, McHugh, Jacalyn, Svendsen, Clive N., Suzuki, Masatoshi
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644484/
https://ncbi.nlm.nih.gov/pubmed/22409357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/17482968.2012.654393
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