GDNF Secreting Human Neural Progenitor Cells Protect Dying Motor Neurons, but Not Their Projection to Muscle, in a Rat Model of Familial ALS

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease characterized by rapid loss of muscle control and eventual paralysis due to the death of large motor neurons in the brain and spinal cord. Growth factors such as glial cell line derived neurotrophic fac...

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Detalhes bibliográficos
Main Authors: Suzuki, Masatoshi, McHugh, Jacalyn, Tork, Craig, Shelley, Brandon, Klein, Sandra M., Aebischer, Patrick, Svendsen, Clive N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925150/
https://ncbi.nlm.nih.gov/pubmed/17668067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000689
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