Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells

Trophic factor delivery to the brain using stem cell-derived neural progenitors is a powerful way to bypass the blood-brain barrier. Protection of diseased neurons using this technology is a promising therapy for neurodegenerative diseases. Glial cell line-derived neurotrophic factor (GDNF) has prov...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Akhtar, Aslam Abbasi, Gowing, Genevieve, Kobritz, Naomi, Savinoff, Steve E., Garcia, Leslie, Saxon, David, Cho, Noell, Kim, Gibum, Tom, Colton M., Park, Hannah, Lawless, George, Shelley, Brandon C., Mattis, Virginia B., Breunig, Joshua J., Svendsen, Clive N.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989694/
https://ncbi.nlm.nih.gov/pubmed/29706501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.024
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