Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells

Trophic factor delivery to the brain using stem cell-derived neural progenitors is a powerful way to bypass the blood-brain barrier. Protection of diseased neurons using this technology is a promising therapy for neurodegenerative diseases. Glial cell line-derived neurotrophic factor (GDNF) has prov...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Akhtar, Aslam Abbasi, Gowing, Genevieve, Kobritz, Naomi, Savinoff, Steve E., Garcia, Leslie, Saxon, David, Cho, Noell, Kim, Gibum, Tom, Colton M., Park, Hannah, Lawless, George, Shelley, Brandon C., Mattis, Virginia B., Breunig, Joshua J., Svendsen, Clive N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018
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Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989694/
https://ncbi.nlm.nih.gov/pubmed/29706501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.024
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