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Construction of Plasmids Containing Site-Specific DNA Interstrand Cross-Links for Biochemical and Cell Biological Studies

Plasmids containing a site-specific DNA interstrand cross-link (ICL) are invaluable tools for the investigation of ICL repair pathways at the biochemical and cellular level. We describe a procedure for preparation of plasmid DNA substrates containing a single ICL at a specific site. The procedure is...

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Main Authors: Enoiu, Milica, Ho, The Vinh, Long, David T., Walter, Johannes C., Schärer, Orlando D.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734532/
https://ncbi.nlm.nih.gov/pubmed/22941606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-998-3_15
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