Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in Melanoma

Nucleotide excision repair (NER) orchestrates the repair of helix distorting DNA damage, induced by both ultraviolet radiation (UVR) and cisplatin. There is evidence that the global genome repair (GGR) arm of NER is dysfunctional in melanoma and it is known to have limited induction in melanoma cell...

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Detalhes bibliográficos
Main Authors: Bowden, Nikola A., Ashton, Katie A., Vilain, Ricardo E., Avery-Kiejda, Kelly A., Davey, Ryan J., Murray, Heather C., Budden, Timothy, Braye, Stephen G., Zhang, Xu Dong, Hersey, Peter, Scott, Rodney J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734271/
https://ncbi.nlm.nih.gov/pubmed/23940574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070424
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