Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in Melanoma

Nucleotide excision repair (NER) orchestrates the repair of helix distorting DNA damage, induced by both ultraviolet radiation (UVR) and cisplatin. There is evidence that the global genome repair (GGR) arm of NER is dysfunctional in melanoma and it is known to have limited induction in melanoma cell...

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Bibliografiske detaljer
Main Authors: Bowden, Nikola A., Ashton, Katie A., Vilain, Ricardo E., Avery-Kiejda, Kelly A., Davey, Ryan J., Murray, Heather C., Budden, Timothy, Braye, Stephen G., Zhang, Xu Dong, Hersey, Peter, Scott, Rodney J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734271/
https://ncbi.nlm.nih.gov/pubmed/23940574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070424
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