Design, Synthesis, Evaluation and Thermodynamics of 1-Substituted Pyridylimidazo[1,5-a]Pyridine Derivatives as Cysteine Protease Inhibitors

Targeting papain family cysteine proteases is one of the novel strategies in the development of chemotherapy for a number of diseases. Novel cysteine protease inhibitors derived from 1-pyridylimidazo[1,5-a]pyridine representing pharmacologically important class of compounds are being reported here f...

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Detalhes bibliográficos
Main Authors: Khan, Mohd Sajid, Baig, Mohd Hassan, Ahmad, Saheem, Siddiqui, Shapi Ahmad, Srivastava, Ashwini Kumar, Srinivasan, Kumar Venkatraman, Ansari, Irfan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734177/
https://ncbi.nlm.nih.gov/pubmed/23940536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069982
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