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CCM1–ICAP-1 complex controls β1 integrin–dependent endothelial contractility and fibronectin remodeling
The endothelial CCM complex regulates blood vessel stability and permeability. Loss-of-function mutations in CCM genes are responsible for human cerebral cavernous malformations (CCMs), which are characterized by clusters of hemorrhagic dilated capillaries composed of endothelium lacking mural cells...
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| Glavni autori: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3734079/ https://ncbi.nlm.nih.gov/pubmed/23918940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303044 |
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