CCM1–ICAP-1 complex controls β1 integrin–dependent endothelial contractility and fibronectin remodeling

The endothelial CCM complex regulates blood vessel stability and permeability. Loss-of-function mutations in CCM genes are responsible for human cerebral cavernous malformations (CCMs), which are characterized by clusters of hemorrhagic dilated capillaries composed of endothelium lacking mural cells...

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Autores principales: Faurobert, Eva, Rome, Claire, Lisowska, Justyna, Manet-Dupé, Sandra, Boulday, Gwénola, Malbouyres, Marilyne, Balland, Martial, Bouin, Anne-Pascale, Kéramidas, Michelle, Bouvard, Daniel, Coll, Jean-Luc, Ruggiero, Florence, Tournier-Lasserve, Elisabeth, Albiges-Rizo, Corinne
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2013
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734079/
https://ncbi.nlm.nih.gov/pubmed/23918940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303044
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