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Kinetic and thermodynamic characterization of the RNA-cleaving 8-17 deoxyribozyme

The 8-17 deoxyribozyme is a small DNA catalyst of significant applicative interest. We have analyzed the kinetic features of a well behaved 8-17 construct and determined the influence of several reaction conditions on such features, providing a basis for further exploration of the deoxyribozyme mech...

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Detalhes bibliográficos
Main Authors: Bonaccio, Maria, Credali, Alfredo, Peracchi, Alessio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373389/
https://ncbi.nlm.nih.gov/pubmed/14963261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh250
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