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Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

In the present study, the relationship between short interfering RNA (siRNA) sequence and RNA interference (RNAi) effect was extensively analyzed using 62 targets of four exogenous and two endogenous genes and three mammalian and Drosophila cells. We present the rules that may govern siRNA sequence...

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Detalhes bibliográficos
Main Authors: Ui-Tei, Kumiko, Naito, Yuki, Takahashi, Fumitaka, Haraguchi, Takeshi, Ohki-Hamazaki, Hiroko, Juni, Aya, Ueda, Ryu, Saigo, Kaoru
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373388/
https://ncbi.nlm.nih.gov/pubmed/14769950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh247
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