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Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

In the present study, the relationship between short interfering RNA (siRNA) sequence and RNA interference (RNAi) effect was extensively analyzed using 62 targets of four exogenous and two endogenous genes and three mammalian and Drosophila cells. We present the rules that may govern siRNA sequence...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ui-Tei, Kumiko, Naito, Yuki, Takahashi, Fumitaka, Haraguchi, Takeshi, Ohki-Hamazaki, Hiroko, Juni, Aya, Ueda, Ryu, Saigo, Kaoru
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC373388/
https://ncbi.nlm.nih.gov/pubmed/14769950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh247
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