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Math5 (Atoh7) gene dosage limits retinal ganglion cell genesis

The basic helix–loop–helix factor Math5 (Atoh7) is critical for the determination of retinal ganglion cell (RGC) fate in mice. Recently, genome-wide association studies have identified the ATOH7 locus as a major determinant of variation in the human optic disc area, which is directly correlated with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Prasov, Lev, Nagy, Melinda, Rudolph, Dellaney D., Glaser, Tom
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733793/
https://ncbi.nlm.nih.gov/pubmed/22660169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e328355f260
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