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Math5 defines the ganglion cell competence state in a subpopulation of retinal progenitor cells exiting the cell cycle

The basic helix-loop-helix (bHLH) transcription factor Math5 (Atoh7) is transiently expressed during early retinal histogenesis and is necessary for retinal ganglion cell (RGC) development. Using nucleoside pulse-chase experiments and clonal analysis, we determined that progenitor cells activate Mat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brzezinski, Joseph A., Prasov, Lev, Glaser, Tom
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337348/
https://ncbi.nlm.nih.gov/pubmed/22445509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.03.006
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