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A Critical Analysis of Atoh7 (Math5) mRNA Splicing in the Developing Mouse Retina

The Math5 (Atoh7) gene is transiently expressed during retinogenesis by progenitors exiting mitosis, and is essential for ganglion cell (RGC) development. Math5 contains a single exon, and its 1.7 kb mRNA encodes a 149-aa polypeptide. Mouse Math5 mutants have essentially no RGCs or optic nerves. Giv...

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Autors principals: Prasov, Lev, Brown, Nadean L., Glaser, Tom
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927423/
https://ncbi.nlm.nih.gov/pubmed/20808762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012315
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