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A Critical Analysis of Atoh7 (Math5) mRNA Splicing in the Developing Mouse Retina

The Math5 (Atoh7) gene is transiently expressed during retinogenesis by progenitors exiting mitosis, and is essential for ganglion cell (RGC) development. Math5 contains a single exon, and its 1.7 kb mRNA encodes a 149-aa polypeptide. Mouse Math5 mutants have essentially no RGCs or optic nerves. Giv...

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Detalhes bibliográficos
Main Authors: Prasov, Lev, Brown, Nadean L., Glaser, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927423/
https://ncbi.nlm.nih.gov/pubmed/20808762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012315
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