Single Administration of Tripeptide α-MSH(11–13) Attenuates Brain Damage by Reduced Inflammation and Apoptosis after Experimental Traumatic Brain Injury in Mice

Following traumatic brain injury (TBI) neuroinflammatory processes promote neuronal cell loss. Alpha-melanocyte-stimulating hormone (α-MSH) is a neuropeptide with immunomodulatory properties, which may offer neuroprotection. Due to short half-life and pigmentary side-effects of α-MSH, the C-terminal...

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Main Authors: Schaible, Eva-Verena, Steinsträßer, Arne, Jahn-Eimermacher, Antje, Luh, Clara, Sebastiani, Anne, Kornes, Frida, Pieter, Dana, Schäfer, Michael K., Engelhard, Kristin, Thal, Serge C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733710/
https://ncbi.nlm.nih.gov/pubmed/23940690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071056
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